Company Profile

From science fiction to science that reads like fiction, the field of cryopreservation has captured the imagination of many. We are fascinated by natural phenomena such as the wood frog (Rana sylvatica), which can freeze during its winter hibernation when 35-45% of the frog's body may turn to ice. Or, for example certain, Antarctic fish that thrive in ice water and tardigrades, tiny 1mm invertebrates that can freeze in winter and completely dry out during the summer.

Core Dynamics is a biotechnology company that is stretching the horizons of the science of cryopreservation. The company is active in the research and development of unique freezing, thawing and freeze drying technologies that are being applied in work with cell preservation, blood transfusion, and tissue and organ transplantation. The company has developed unique protocols, equipment and solutions for cryopreservation of cells, of tissues such as osteo-articular cartilage and of whole organs.

Core Dynamics hopes to develop additional applications through research partnerships involving its advanced cryopreservation technologies.

Core Dynamics' Research and Development center is located in Ness Ziona, Israel, with a staff of over 30 research scientists and support personnel. Company management has wide experience in the fields of medicine, cryopreservation and cell biology. The company's commercial offices are located in Rockville, Maryland.

Research in Freezing, Thawing and Freeze-Drying

Core Dynamics' research has led to the successful freezing and lyophilization of white blood cells and stem cells. The ability to preserve and store cells at room temperature, thereby negating the logistical problems involved in transportation and storage in freezers and liquid nitrogen will open a world of possibilities for research and work with many varieties of cells.

Applying the company's MTG freezing technology and freezing protocols to cartilage has led to the successful long term preservation of osteo-articular allograft plugs. In a series of clinical trials over the past year preserved plugs have been transplanted in patients suffering from cartilage damage in the knee. 

In the area of whole organs Core Dynamics has successfully transplanted frozen thawed ovaries in large animals. In the near future this technology will be applied to human ovaries for the purpose of fertility preservation in young female patients undergoing chemo and radiotherapy.

Core Dynamics is confident that supplies of lyophilized (freeze dried) cells and preserved tissues and organs screened for contamination will revolutionize the field of cell therapy, the blood transfusion and transplantation industries and other research involving a wide variety of cells.